Publications by authors named "Jennifer C Whitesell"
Page 1 of 1
Synopsis of recent research by authors named "Jennifer C Whitesell"
- Jennifer C Whitesell's research primarily focuses on the immune response mechanisms involved in the development and progression of autoimmune diseases, particularly type 1 diabetes and islet inflammation (insulitis) in NOD mice.
- Recent studies reveal that the phenotypic characteristics and regulatory roles of islet lymphocytes are crucial under both homeostatic conditions and during metabolic stress, emphasizing their importance in the inflammatory response within pancreatic islets.
- Whitesell's work also highlights the role of specific immune cells, such as mononuclear phagocytes and CD11c cells, in mediating T cell regulation and trafficking to islets, which is key for understanding the autoimmune attack in type 1 diabetes.
