Publications by authors named "Jennifer Blickwedehl"
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Synopsis of recent research by authors named "Jennifer Blickwedehl"
- Jennifer Blickwedehl's research primarily focuses on the roles of proteasome activators, such as PA200, in cellular responses to stressors like ionizing radiation and therapeutic agents in cancer cells.
- Findings suggest that PA200 enhances cellular survival and genomic stability following ionizing radiation by increasing proteasome activity, indicating its critical role in cellular repair mechanisms.
- Additionally, her studies on bortezomib reveal distinct molecular mechanisms behind the drug's effectiveness in therapy-resistant versus therapy-sensitive B-cell non-Hodgkin lymphoma, emphasizing the importance of understanding cell-specific responses in cancer treatment.