"That's the price of living in paradise:" coastal retirement and hurricanes.

Coastal Carolina is a popular retirement destination. Ten individuals, previously interviewed regarding their decision to retire here, were re-interviewed after Hurricane Florence. This sample of eight women and two men, mean age 74.

Professional development in integrative health through an interprofessional online course in clinical settings.

Background: Although there is mounting clinical and cost-effectiveness evidence supporting integrative healthcare (IH), a significant knowledge gap hinders widespread adoption by health professionals.

Intervention: Foundations in Integrative Health (FIH), a 32-h online competency-based interprofessional course to address this knowledge gap.

Methods: The course was pilot-tested by an interprofessional sample of providers in various clinical settings as professional and staff development.

Sequence capture phylogenomics of eyeless spiders from Texas caves, with emphasis on US federally-endangered species from Bexar County (Araneae, Hahniidae).

Morphological, mitochondrial, and nuclear phylogenomic data were combined to address phylogenetic and species delimitation questions in cave-limited spiders from central Texas. Special effort was focused on specimens and cave locations in the San Antonio region (Bexar County), home to four eyeless species listed as US Federally Endangered. Sequence capture experiments resulted in the recovery of ~200-400 homologous ultra-conserved element (UCE) nuclear loci across taxa, and nearly complete COI mitochondrial DNA sequences from the same set of individuals.

Efficacy of early treatment in patients with cobalamin C disease identified by newborn screening: a 16-year experience.

Purpose: Despite implementation of newborn screening (NBS), outcomes in cobalamin C disease (cblC) remain poor. Therapy with hydroxycobalamin and betaine is widely used, but dietary recommendations vary among metabolic centers. We present a longitudinal analysis of the relationship between metabolic control, diet, and outcomes in a cohort of cblC patients.

Bumblefoot: a comparison of clinical presentation and treatment of pododermatitis in rabbits, rodents, and birds.

Pododermatitis, also known as bumblefoot, is a common condition encountered in birds, rabbits, and rodents in clinical practice. This article compares the anatomy and physiology of the foot and the predisposing factors for pododermatitis in each of the species discussed. Clinical presentation, diagnostics, and treatment options, including medical and surgical therapies, are provided.

Introduction to traditional Asian therapeutic diets: two enduring perspectives.

In some ancient systems of medicine, health was understood as a state of balance, and diet was considered essential to achieving and maintaining that balance. Traditional Chinese medicine and Ayurveda are based on this premise. Here we present an overview of these two traditional systems' views on diet and eating.

In vivo characterization of 6beta-naltrexol, an opioid ligand with less inverse agonist activity compared with naltrexone and naloxone in opioid-dependent mice.

The mu-opioid receptor displays basal signaling activity, which seems to be enhanced by exposure to opioid agonists. This study assesses the in vivo pharmacology of the putative "neutral" antagonist 6beta-naltrexol in comparison to other ligands with varying efficacy, such as naloxone, an inverse agonist in the opioid-dependent state. ICR mice were used to generate full antagonist dose-response curves for naloxone, naltrexone, nalbuphine, and 6beta-naltrexol in blocking acute antinociceptive effects of morphine and precipitating opioid withdrawal in models of physical dependence.

Electrocardiographic changes in children and adolescents treated with ziprasidone: a prospective study.

Objective: To assess the electrocardiographic safety profile of low-dose ziprasidone (< or =40 mg/day) among pediatric outpatients treated for up to 6 months.

Method: This was a prospective, open-label trial involving 20 subjects with a mean age of 13.2 +/- 3.