Evaluation of a Pharmacist-Developed, Nurse-Driven Protocol for Management of Parenteral Anticancer Therapy Infusion Reactions in an Ambulatory Infusion Center.

Purpose: Intravenous anticancer therapy can be associated with hypersensitivity- and/or infusion-related reactions (IRRs) which may result in life-threatening symptoms. As part of a quality improvement project, oncology pharmacists developed and implemented a nurse-driven, symptom-based IRR protocol. The objective of the evaluation was to evaluate IRR treatment failure after implementation of a symptom-based protocol in an ambulatory infusion center.

Evaluation of Treatment-Dose Enoxaparin in Acutely Ill Morbidly Obese Patients at an Academic Medical Center: A Randomized Clinical Trial.

Background: Enoxaparin dosing recommendations for morbidly obese patients are lacking. Retrospective and observational studies reported goal anti-Xa levels with a median dose of 0.8 mg/kg using total body weight.

Analysis of Opioid Use Following Curative Cancer Treatment at a Large Urban Safety-net Hospital.

Objectives: This study examined the pattern of use and factors predicting prolonged prescription opioid medications among cancer patients following treatment with curative intent.

Materials And Methods: Patients diagnosed with cancer over a 3-year period at a large urban safety-net hospital were included. Univariate and multivariate analyses was used to identify factors associated with continued opioid use.

Antibiotic allergies in the medical record: effect on drug selection and assessment of validity.

Study Objectives: To determine the frequency with which reported antibiotic allergies alter drug selection and to assess the validity of these allergies.

Design: Retrospective medical record review, with concurrent interviews conducted in a selected subgroup of patients.

Setting: Tertiary care academic medical center.