Publications by authors named "Jennie Z Li"
Neural Regen Res
January 2025
Article Synopsis
- Alzheimer's disease is a chronic neurodegenerative disorder that leads to dementia, primarily caused by the accumulation of amyloid-β oligomers, influenced by genetic and environmental factors.
- Memory deficits in the early stages of the disease are linked to synaptic dysfunction, and environmental influences can cause lasting changes in gene expression through epigenetic modifications.
- Recent research emphasizes the importance of epigenetic factors like DNA methylation and histone modification in Alzheimer's progression, and suggests tailored therapeutic strategies that target specific disease stages for better management rather than one-size-fits-all treatments.
