Perspective: Women's leadership and salary inequality in sleep medicine.

Unlabelled: Gender inequity exists within medicine in both compensation and leadership positions. In this perspective, the data on American Academy of Sleep Medicine leadership positions held by women and compensation differences between men and women physicians in an American Academy of Sleep Medicine compensation survey were studied. The results showed significant improvement in the inclusivity of women in senior-level leadership.

O-GlcNAcylation regulates extracellular signal-regulated kinase (ERK) activation in Alzheimer's disease.

Introduction: Aberrant activation of Extracellular Signal-Regulated Kinase (ERK) signaling is associated with Alzheimer's disease (AD) pathogenesis. For example, enhanced ERK signal activation mediated by Apolipoprotein E4 (APOE4), which is a critical genetic risk factor for AD, increases the transcription of amyloid precursor protein (APP). We hypothesize that O-linked N-acetylglucosamine (O-GlcNAc) regulates the phosphorylation and activation of ERK.