Insulin infusion reduces hepatocyte growth factor in lean humans.

Objective: Plasma Hepatocyte Growth Factor (HGF) is significantly elevated in obesity and may contribute to vascular disease, metabolic syndrome or cancer in obese individuals. The current studies were done to determine if hyperinsulinemia increases plasma HGF.

Materials/methods: Twenty-two participants (10 women/12 men, BMI 20.

Serum markers of bone turnover are increased at six and 18 months after Roux-en-Y bariatric surgery: correlation with the reduction in leptin.

Objective: The aim of the study was to examine serum markers of bone turnover at 6 and 18 months after Roux-en-Y gastric bypass surgery.

Participants: Ten women and 10 men [body mass index (BMI), 50.2 +/- 8.