Publications by authors named "Jenna O'Sullivan"
Calcific constrictive pericarditis following tumour necrosis factor-alpha inhibition.
Eur Heart J Case Rep
February 2024
Article Synopsis
- - Tumour necrosis factor (TNF)-alpha inhibitors like adalimumab are commonly used to treat inflammatory and autoimmune disorders, but they can lead to side effects, including rare cardiac complications such as pericarditis.
- - A 63-year-old woman on adalimumab for hidradenitis suppurativa experienced increased breathlessness, with tests revealing pericardial calcification and constrictive pericarditis, leading to surgical intervention after cardiac failure.
- - This case suggests that long-term adalimumab therapy could be linked to unusual cardiac issues, like calcific constrictive pericarditis, challenging the notion that such complications are solely linked to traditional causes.
A 22-year-old woman was referred with exertional dyspnoea and chest tightness 3 weeks following a diagnosis of COVID-19. Evaluation revealed a resting sinus tachycardia and criteria for postural orthostatic tachycardia syndrome were met. After non-pharmacological interventions failed to yield symptomatic improvement, ivabradine was commenced.
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