Publications by authors named "Jenna Garofolo"
Article Synopsis
- Light-activated compounds, especially ruthenium polypyridyl complexes, have medical potential by allowing control of biological effects through light activation, inducing cytotoxicity in targeted treatments.
- A study on various Ru(II) complexes showed that those with strain-inducing methyl groups could bond to biomolecules upon light activation, while unstrained complexes primarily generated reactive oxygen species (ROS).
- Results indicated that strained complexes were more photoactive and cytotoxic than their unstrained counterparts, with specific ligand modifications enhancing activation by red light and photolabile complexes proving to be more effective in killing cells.
