Publications by authors named "Jeng-Wen Huang"
Article Synopsis
- This study investigates methods to predict rapid progressors (RPs) in patients with autosomal dominant polycystic kidney disease (ADPKD) in the Asia-Pacific region, involving five hospitals from different countries.
- Results showed that, out of 768 patients, 426 were identified as RPs, with significant occurrences of kidney-related complications and a higher rate of progression to end-stage kidney disease (ESKD) compared to slow progressors (SPs).
- The strongest predictor of RP was historical decline in estimated glomerular filtration rate (eGFR), suggesting the need for varied assessment strategies in clinical practice for better identification of RPs among ADPKD patients.
Liposomes have been used to improve therapeutic efficacy of drugs by increasing their bioavailability and altering biodistribution. The loading capacity of small molecules in liposomes remains a critical issue. Besides, the manufacturing process of liposomes requires multi-step procedures which hinders the clinical development.
View Article and Find Full Text PDFBackground: To assess whether angiotensin-II receptor blockers (ARBs) offer any additional advantage in confirming the diagnosis of primary aldosteronism (PA) and their use in the differentiation of PA subtypes.
Methods: A prospective, cohort, head-to-head study was conducted between July 2003 and July 2006. A total of 135 patients received captopril and losartan tests to confirm the diagnosis of PA in the TAIPAI (Taiwan Primary Aldosteronism Investigation) intervention.
Aim: Patients with end-stage renal disease (ESRD) often start long-term haemodialysis (HD) thrice weekly, regardless of the level of residual renal function (RRF). In this study, we investigated whether ESRD patients having sufficient RRF can be maintained on twice-weekly HD, and how they fare compared to patients without RRF on thrice-weekly HD.
Methods: We analyzed 74 patients who had undergone long-term HD and maintained on the same dialysis frequency from February 1998 to July 2005, and followed until December 2005.
Background: Malnutrition-inflammation score (MIS) is a comprehensive and quantitative system to assess malnutrition-inflammation complex syndrome, and a strong correlation between MIS and morbidity/mortality in maintenance hemodialysis (MHD) patients had been demonstrated. However, there is no cut-off value of MIS to categorize patients into high risk or low risk patients.
Methods: A total of 257 chronic stable and ambulatory adult MHD patients from Far Eastern Memorial Hospital were enrolled for the study.