Publications by authors named "Jeng-Hwan Wang"
Adjuvants can be used to enhance the immunogenicity of antigens and improve the efficacy of vaccines. Potent adjuvant action is known to often correlate with the activation of the transcription factor, nuclear factor-κB (NF-κB). Specific plant polysaccharides and a variety of phytochemicals from foods and traditional medicinal herbs have been shown to modulate NF-κB activation.
View Article and Find Full Text PDFBackground: Foot-and-mouth disease virus (FMDV) causes a severe livestock disease, and the virus is an interesting target for virology and vaccine studies.
Materials And Methods: Here we evaluated comparatively three different viral antigen-encoding DNA sequences, delivered via two physical means (i.e.
Article Synopsis
- VP1 is a protein from the foot-and-mouth disease virus that has important neutralizing parts but is hard to dissolve in water.
- Researchers managed to purify this protein in two forms—monomer and dimer—by using a method that involved protein refolding and removing detergents.
- Immunization tests showed that both forms of the protein effectively triggered immune responses in pigs and provided protection against the disease.