Sublethal urea exposure in Nile tilapia: Morphological, behavioural, and histological alteration.

The pace of research efforts has been extraordinarily accelerated across the globe to address the contamination issues caused by pesticides, and fertilizers, especially in the aquatic ecosystem. The sole aim of this study was to assess the effect of urea on Nile tilapia (Oreochromis niloticus). For this purpose, the fish fingerlings were exposed to increasing concentrations of urea such as 0, 1, 2.

Advancing sustainable agriculture: Evaluation of Poly (lactic acid) (PLA) based mulch films and identification of biodegrading microorganisms among soil microbiota.

Non-biodegradable polyolefin based plastic mulch residues in agricultural fields after the end of a crop cycle have raised several concerns as an environmental pollutant in recent years. This study explores the potential of Poly (lactic acid) (PLA) and Poly (butylene adipate-co-terephthalate) (PBAT) based compostable films reactively blended with compatibilizers and chain extenders as a promising solution to environmental challenges associated with traditional plastic mulch films. Epoxidized soybean oil (ESO) and Epoxy-functionalized styrene acrylic copolymer (ESA) have been used as reactive compatibilizers and chain extenders respectively.

Room temperature exciton formation and robust optical properties of CVD-grown ultrathin BiOSe crystals on arbitrary substrates.

The appealing success of non-van der Waals (non-VdW) two-dimensional (2D) bismuth oxyselenide (BiOSe) crystals in optoelectronics provides an exciting avenue to investigate their fundamental physical properties. To date, the majority of efforts have focused on understanding the properties of 2D BiOSe, usually grown on a mica substrate. However, a gap exists in realizing the origin of photoluminescence (PL) of new age non-VdW BiOSe at visible and near-infrared (NIR) wavelengths and the effect of growth substrates on the structure and optical properties.

Solvent controlled synthesis of 2,3-diarylepoxy indenones and α-hydroxy diarylindanones and their evaluation as inhibitors of DNA alkylation repair.

Herein, we report a novel and unexpected metal-free oxygenation of 2,3-diphenyl-1-indenones, under an oxygen atmosphere (air), to either 2,3-epoxy-2,3-diphenyl-1-indenone or 2-hydroxy-2,3-diphenyl-1-indanone, depending on the conditions. Several bioactive epoxy indenones and one-pot α-hydroxy indanones (α-acyloin) were synthesized from 2,3-diaryl dihydroindanone and 2,3-diarylindenone, respectively. A plausible reaction mechanism is also proposed, where oxygenation would take place at the α-position and further proton abstraction from the β-position leads to epoxy indenone derivatives.

Alkyl Enol Ethers: Development in Intermolecular Organic Transformation.

Alkyl enol ethers (AEE) are versatile synthetic intermediates with a unique reactivity pattern. This review article summarizes the synthesis of AEE as well as its reactivity and how enol ether undergoes intermolecular reactions for various bond formation, leading to the construction of several useful organic molecules. The synthetic applications of alkyl enol ethers towards intermolecular bond-forming reactions include metal-catalyzed reactions, cycloaddition and heterocycle formation as well as rwactions in the field of natural products synthesis.

Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues.

Marine sponges of the genusSuberea produce variety of brominated tyrosine alkaloids which display diverse range of biological activities including antiproliferative, antimicrobial and antimalarial activities. In continuation of our search for biologically active marine natural products for antibacterial compounds, we report here the synthesis and evaluation of biological activity of panel of ianthelliformisamines and subereamine analogues using the literature known acid-amine coupling reaction. Several derivatives of Ianthelliformisamine were achieved by the coupling of Boc-protected polyamine chain with brominated aromatic acrylic acid derivatives by varying the bromine substituents on aromatic acid derivatives, amine spacer as well as geometry of the double bond, and then Boc-deprotection using TFA.

Direct α-Benzylation of Methyl Enol Ethers with Activated Benzyl Alcohols: Its Rearrangement and Access to (±)-Tetrahydronyasol, Propterol A, and 1,3-Diarylpropane.

Herein, we report a one-pot Lewis acid mediated synthesis of bi- and triarylpropanal derivatives and their corresponding isomeric ketones from aromatic enol ethers. This transformation takes place via nucleophilic attack of enol ethers to electron-rich benzyl alcohols. The substrate scope of this indicates that it might proceed via quinomethoxy methide as a key intermediate leading to propanal derivatives, and their Wagner-Meerwein rearrangement afforded isomeric ketones.

The effects of Donepezil on traumatic brain injury acute rehabilitation outcomes.

Primary Objective: To evaluate the effects of administering Donepezil during inpatient rehabilitation for individuals with TBI.

Research Design: Retrospective, age and injury severity matched, mixed between-within subjects analysis.

Methods And Procedures: Thirty-six patients with moderate-to-severe TBI admitted to acute rehabilitation within 90 days of injury.

Non-linear law-like relationship between weight & height of infants & pre-school children.

A non-linear equation of the type log w - 0.008 h = a - be-kl for weight (w) and height (h) of 1177 infants and pre-school children from the Rural Health Centre area in Ballabhgarh was fitted by modified Guass-Newton Method using BMDP 03R program. On applying the non-linear model to the data of the present study it was found that the curve was a good fit in both sexes and also in all nutritional groups.

Age at which chest circumference overtakes head circumference in children.

Maximum likelihood method with probit transformation was applied to estimate median age at which chest circumference (CC) overtook head circumference (HC) in 1206 children from rural areas of Ballabhgarh in Haryana and in 1505 children from a slum population in Delhi. The results showed that, in case of rural area, this phenomenon occurred at an average age of 31.36 months and in children from urban slums, at an average age of 28 months.