Synopsis of recent research by authors named "Jen-Ruey Tang"
Jen-Ruey Tang's research primarily focuses on understanding the mechanisms behind lung development and dysfunction, particularly in the context of neonatal pulmonary conditions such as bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH).
Key findings include the identification of oxidative stress and inflammatory responses as crucial factors impairing lung growth and vascular development in various animal models, pointing to the importance of signaling pathways like VEGF and NF-κB.
The research also explores potential therapeutic interventions, such as inhaled nitric oxide (iNO) treatment, which has shown promise in ameliorating lung damage and supporting growth in preterm models exposed to detrimental conditions.
