Publications by authors named "Jen-Chen Cheng"
Article Synopsis
- The study investigates the role of JMJD5, a histone demethylase, in tumor growth and metastasis for patients with oral squamous cell carcinoma (OSCC), finding that higher JMJD5 levels correlate with larger tumors and worse survival rates.
- It explores the anticancer effects of silibinin, a drug known for its hepatoprotective properties, which shows promise in inhibiting tumor growth and downregulating JMJD5 in both lab studies and mouse models with patient-derived tumors.
- The research highlights that JMJD5 may serve as a valuable prognostic marker for OSCC and suggests that targeting JMJD5 with silibinin, possibly via the MTA1 pathway, could be a novel approach in
