A conserved transcriptional fingerprint of multi-neurotransmitter neurons necessary for social behavior.

Background: An essential determinant of a neuron's functionality is its neurotransmitter phenotype. We previously identified a defined subpopulation of cholinergic neurons required for social orienting behavior in zebrafish.

Results: We transcriptionally profiled these neurons and discovered that they are capable of synthesizing both acetylcholine and GABA.