Assessment of fluoride bio-accessibility in early childhood diets.

Introduction: Currently available dietary recommendations for fluoride provided as "adequate intake" (AI) and "tolerable upper intake level" (UL) assume 100% fluoride availability for utilization by the body, which is often not the case. To prevent the development of dental fluorosis, AI and UL values must include fluoride bioavailability. However, the lack of data on fluoride bioavailability/bio-accessibility has hindered progress so far.