Effects of hormone replacement therapy on depressive and anxiety symptoms after oophorectomy.

Aim: To assess the effect of hormone replacement therapy on postoperative depression and anxiety symptoms.

Methods: In observational prospective study 80 women divided into two groups were evaluated: women who received estrogen and androgen replacement therapy after hysterectomy with bilateral oophorectomy before onset of menopause (35-45 years old) and a control group that consisted of perimenipausal women (45-55 years old). Hormone replacement therapy began one week after surgery.