Ultrastructure of Hyperfunctioning Parathyroid Glands: Does it Explain Various Patterns of Tc-sestamibi Uptake.

The aim of this study was to correlate the uptake of Tc-methoxy-isobutyl-isonitrile (MIBI) with ultra-structural features of parathyroid adenomas. Twenty patients with proven primary hyperparathyroidism were evaluated prospectively. Preoperative double-phase Tc-MIBI scintigraphy was performed in all patients and the degree of tracer uptake by the parathyroid lesions was assessed visually and semi-quantitatively.