Sexual behaviour and risk compensation among single women of reproductive age using hormonal contraception in Zambia.

Objective: Developing countries have seen an increase in the use of hormonal contraception due to its high efficacy in preventing pregnancy. Our study assessed risk compensation among single women of reproductive age using hormonal contraception.

Methods: The study used data from a nationally representative, cross-sectional sample of the 2018 Zambia Demographic and Health Survey (DHS).

Renal histopathological and biochemical changes following adjuvant intervention of and antiretroviral therapy in diabetic rats.

Objectives: Diabetic nephropathy (DN) is an important primary cause of end-stage kidney disease. This study explores the mechanisms of the reno-protective effects of () in diabetic rats following treatment with highly active antiretroviral therapy (HAART) regimen triplavar.

Materials And Methods: Adult male Sprague-Dawley rats (n=48) were divided into 7 groups (A-G).

Nephrotoxicity and highly active antiretroviral therapy: Mitigating action of .

() is known for its antioxidant and antidiabetic properties. The aim of this study is to investigate the renoprotective effects of in rats following treatment with highly active antiretroviral therapy (HAART) regimen triplavar. Adult male Sprague-Dawley rats weighing 178.

alters metabolic parameters and hepatic histomorphology in streptozotocin-nicotinamide-induced diabetic male rats under antiretroviral therapy.

Introduction: Highly active antiretroviral therapy (HAART) and HIV/AIDS have been demonstrated to induce endocrine/metabolic dysfunction with a consequential increase in morbidity/mortality due to organ toxicities. This study aimed at investigating the possible protective effect of () against metabolic and hepatic histomorphology of diabetic rats under HAART.

Material And Methods: Sixty-two adult male Sprague-Dawley rats were divided into a normoglycemic group A ( = 6) and 7 diabetic (110 mg/kg nicotinamide + 45 mg/kg streptozotocin) groups (B-H) ( = 8) and treated according to protocols.

Impaired expression of testicular androgen receptor and collagen fibers in the testis of diabetic rats under HAART: the role of Hypoxis hemerocallidea.

Introduction: Wide spectrum of alterations associated with highly active antiretroviral therapy (HAART) has been reported. The current study aimed at evaluating the role of Hypoxis hemerocallidea (HH) aqueous extract on the testosterone levels, expression of androgen receptors and collagen fibers in the testes of streptozoto-cin-nicotinamide-induced diabetic rats under HAART regimen.

Material And Methods: Sixty two adult male Sprague-Dawley rats (189.

Hepatic histomorphological and biochemical changes following highly active antiretroviral therapy in an experimental animal model: Does exacerbate hepatic injury?

As the roll-out of antiretroviral therapy continues to drive downwards morbidity and mortality in people living with HIV/AIDS (PLWHAs), organ toxicities (especially the liver) are frequently becoming a major concern for researchers, scientists and healthcare planners. This study was conducted to investigate the possible protective effect of (AP) against highly active antiretroviral therapy (HAART)-induced hepatotoxicity. A total of 63 pathogen-free adult male Sprague-Dawley rats were divided into 9 groups and treated according to protocols.