Coculture with Late, but Not Early, Human Endothelial Progenitor Cells Up Regulates IL-1 β Expression in THP-1 Monocytic Cells in a Paracrine Manner.

Endothelial progenitor cells (EPCs) have been used in clinical trials to treat ischemic heart disease. Monocyte infiltration plays an important role in inflammation, angiogenesis, and tissue repair during tissue ischemia. It is important to understand the interactions between EPCs and monocytes.