Publications by authors named "Jeffrey S Hardesty"

Purpose: Intravesical electrical stimulation treatment (IVES) has been successfully used to treat neurogenic bladder. We report the results of an observational study regarding the use of IVES for women with overactive bladder syndrome (OAB) and/or urgency urinary incontinence (UUI).

Materials And Methods: IVES was performed in women with OAB (defined by frequency ≥8/day, nocturia ≥2/night, or ≥3 episodes of UUI on 3-day voiding diary) who failed prior medical therapy.

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Article Synopsis
  • Postoperative urinary retention occurs in 13-32% of patients after pelvic organ prolapse (POP) repair, prompting this study to compare retention rates between transvaginal and robotic approaches while identifying risk factors.
  • Out of 484 patients, 26.4% experienced urinary retention, with a significantly higher occurrence in those undergoing transvaginal high uterosacral ligament suspension (HUSLS) compared to robotic-assisted sacral colpopexy (RASCP), showing an odds ratio of 3.26 for transvaginal HUSLS.
  • Older age was identified as a significant risk factor for urinary retention, while factors like parity and preoperative post-void residual were not significant in multivariate analysis.
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Unlabelled: The optimal degree of cystoscope to perform diagnostic cystoscopy is dependent on the surgeon's discretion because there are no studies addressing the superiority of one degree of cystoscope over another. The objective was to determine which lens, 70-degree versus 30-degree lens, was better in identifying lesions scattered throughout the bladder.

Methods: A simulation was created using 3 different artificial bladder models complete with sutures representing lesions placed at different locations in each bladder.

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Purpose: To illustrate a simple method that screens for ureteral injury in the acute postoperative period after urogynecologic surgeries.

Methods: Serum creatinine measurements in the preoperative (baseline) and postoperative periods of urogynecologic surgeries were determined and the correlation of the change to ureteral injury and/or obstruction analyzed. The sample size calculation showed 7 cases and 28 controls were sufficient to detect significant changes in creatinine.

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Purpose: To determine the optimal riboflavin exposure time before UVA irradiation and to study the effects of exogenous collagen on the mechano-tensile stiffness of isolated vaginal tissue strips after riboflavin UVA photoactivation.

Methods: Vaginal tissue strips from pelvic organ prolapse (POP) cases were soaked in 0.1% riboflavin (0, 10, 20, 30 min), exposed to UVA photoactivation, and tensile stiffness was measured with a tensiometer.

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Background: The pathophysiology of pelvic organ prolapse (POP) involves vaginal collagen degradation. Strengthening collagen by UVA-photoactivated cross-linking has been demonstrated and suggested target applications include the vaginal wall.

Aim: To identify UVA irradiation and riboflavin effects on vaginal cells.

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