Publications by authors named "Jeffrey Leon-Pulido"

Enhancing the biochemical supply chain towards sustainable development requires more efforts to boost technology innovation at early design phases and avoid delays in industrial biotechnology growth. Such a transformation requires a comprehensive step-wise procedure to guide bioprocess development from laboratory protocols to commercialization. This study introduces a process design framework to guide research and development (R&D) through this journey, bearing in mind the particular challenges of bioprocess modeling.

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Article Synopsis
  • * The production process involves synthesizing TiO nanoparticles from lemongrass oil and titanium isopropoxide in a two-stage process, aiming for an annual output of 2033 tons.
  • * The results indicate that the process faces significant risks, especially concerning the handling of titanium isopropoxide, which is toxic and flammable, leading to a global safety score of 28, reflecting higher risks than industry standards.
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Recently, exergy analysis has attracted great attention of the scientific community as an attractive tool for evaluating energetic efficiency of any process. In this work, the simulation of the amine treatment unit in a Latin-American refinery was performed in order to apply the exergy analysis tool to identify alternatives of improvement. The industrial amine treatment unit was simulated using Aspen plus software, which provided extended energy and mass balances.

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