Publications by authors named "Jeffrey Justin Estella"
Article Synopsis
- The study investigates the effectiveness of targeted next generation sequencing (NGS) for identifying chromosomal abnormalities in patients with myeloid neoplasms using plasma cell-free DNA (cfDNA) samples from 2821 patients.
- Results showed that 54.5% of samples had mutations associated with neoplasms, with distinct rates of abnormalities observed in myeloid (59%) and lymphoid (41%) neoplasms, and a strong concordance between cfDNA NGS results and traditional bone marrow cytogenetic data.
- The research concludes that liquid biopsy through targeted NGS is a reliable method for detecting chromosomal abnormalities, potentially offering an alternative to invasive bone marrow biopsies for monitoring
