Anti-inflammatory activity of sappan wood extract cream () in -induced gingivitis rats models.

Background: Gingivitis is a dysbiotic condition characterized by persistent inflammation caused by a disease-associated multispecies bacterial population that has established itself in the subgingival region.

Aim: The objectives of this study are to analyze the anti-inflammatory activity of sappan wood extract cream (SWC) in induced-periodontitis rats model.

Methods: In this study, rats were infected with the gingiva with as an inducer for gingivitis rats model for 14 days.

Brazilin cream from inhibit periodontal disease: study.

Background: Gingivitis is an inflammation of the gums that is the initial cause of the development of periodontal disease by the activity of Nuclear Factor-kappa B (NF-κB), Interleukin-1β (IL-1β), Interleukin-6 (IL-6), p38, and Tumor Necrosis Factor-α (TNF-α). Unaddressed chronic inflammation can lead to persistent disturbances in other parts of the body. Brazilin is a naturally occurring plant chemical that may have antibacterial and anti-inflammatory effects.