Publications by authors named "Jeffrey J McCullough"
Article Synopsis
- The text outlines updated evidence-based guidelines from ASCO regarding platelet transfusion practices for cancer patients, replacing guidelines from 2001.
- The update involved a systematic review of literature from 2014 to 2016, including insights from other organizations like AABB, focusing on areas not fully covered previously.
- Major changes include allowing adult patients undergoing autologous stem-cell transplantation to receive transfusions at the first sign of bleeding instead of preemptively, while maintaining prophylactic transfusions for certain pediatric and allogeneic patients.
Introduction: Available literature suggests there is a transient drop in implant stability from approximately week 0 to week 3-4 as a result of peri-implant bone remodeling as it transitions from a primary, mechanical stability to a secondary, biological stability. Research investigating the influence of macro-thread design on this process is scant.
Aim: The specific aim of this study was to evaluate the role of macro-thread design on implant stability in the early post-operative healing period using resonance frequency analysis (RFA).
Background: During the Trial to Reduce Alloimmunization to Platelets (TRAP Trial), data were prospectively collected for 8769 PLT transfusions regarding the frequency of moderate to severe PLT transfusion reactions.
Study Design And Methods: At seven centers, 598 patients were randomly assigned to receive unmodified pooled random-donor PLT concentrates (PCs), UV-B-irradiated PCs, filtered PCs, or filtered random-donor apheresis PLTs.
Results: Moderate to severe transfusion reactions were an increase in temperature of at least 2 degrees C, chills with rigors, extensive urticaria, dyspnea, cyanosis, or bronchospasm.