IgG4-related intracranial disease.

IgG4-related disease (IgG4-RD) is a multi-organ chronic inflammatory process caused by infiltration of IgG4-positive plasma cells in one or more organs. Intracranial involvement has only recently become better recognized. Our case series adds to the growing literature on the varying presentations of intracranial IgG4 by describing the clinical and imaging findings of three patients who presented to our institution with intracranial involvement.

Peer Review in Radiology: A Resident and Fellow Perspective.

Purpose: The purpose of this study was to explore Canadian radiology residents' and fellows' understanding, attitudes, opinions, and preferences toward peer review.

Methods: An Internet-based anonymous questionnaire designed to understand one's familiarity, attitudes, opinions, and preferences toward peer review was distributed to radiology residents and fellows across Canada. Data were analyzed using descriptive statistics, and answers were stratified by level of training.

Endovascular first strategy for de novo TransAtlantic Inter-Society Consensus C and D femoro-popliteal disease: mid-term outcomes from a single tertiary referral center.

Purpose: Describe outcomes after endovascular intervention of TransAtlantic Inter-Society Consensus C and D femoro-popliteal disease.

Materials And Methods: Retrospective cohort study. Patient demographics, ankle-brachial indices, and lesion details were analyzed from a prospectively maintained database.

Bridging stent-graft pullout force analysis.

Purpose: To assess the pullout force (POF) of bridging stent-grafts used in thoracoabdominal stent-grafts and iliac bifurcated grafts.

Methods: In an experimental setup, the POFs of Viabahn or Fluency with or without a Zilver stent were measured when deployed into the renal and celiac branches of a Zenith thoracoabdominal cuff-bearing branched stent-graft. The POFs of the Atrium i-Cast, Viabahn, Fluency, and Fluency+Zilver were measured when deployed into an iliac bifurcated graft with a short side-branch for the internal iliac artery.

The E646D-ATP13A4 mutation associated with autism reveals a defect in calcium regulation.

ATP13A4 is a member of the subfamily of P5-type ATPases. P5-type ATPases are the least studied of the P-type ATPase subfamilies with no ion specificities assigned to them. In order to elucidate ATP13A4 function, we studied the protein's subcellular localization and tested whether it is involved in calcium regulation.