Integrative bioinformatics: making sense of the networks.

The focus of biology has shifted from the investigation of individual genes and proteins to the study of large complex networks featuring interactions between tens of thousands of molecular and cellular components. Information on these networks is obtained from genome-scale experimental and theoretical analyses, which yield valuable but noisy data, on biological processes that are still poorly understood. The new exciting developments in bioinformatics show great promise in meeting the challenge of extracting biological insight from these data.