Publications by authors named "Jeffrey Breton"

Article Synopsis
  • TCPs (transitional care protocols) can significantly improve discharge outcomes for patients undergoing elective neurosurgery, leading to higher rates of home discharges and reduced hospital stays.
  • The review analyzed 16 studies, revealing a notable decrease in readmission rates, emergency department visits, and overall length of hospital stays for patients who had TCPs implemented.
  • Overall, the findings suggest that implementing TCPs in elective neurosurgery settings may enhance patient satisfaction and safety, ultimately alleviating the strain on healthcare systems.
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Spinal arachnoid web (AW) is a rare condition causing spinal cord-related issues. Its cause is often idiopathic but can be linked to past trauma or spine surgery. We describe two cases of AWs that developed after subarachnoid hemorrhage (SAH).

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Article Synopsis
  • - A 43-year-old male with a history of T-cell lymphoma and high-risk polycythemia vera (PCV) experienced severe lower-back pain that radiated to his legs, along with weakness and an enlarged spleen.
  • - MRI scans showed multiple epidural lesions causing severe spinal canal stenosis, leading to surgical decompression, which relieved his leg pain and weakness.
  • - Biopsy indicated extramedullary hematopoiesis (EMH) resembling a spinal tumor; he received palliative radiation and other treatments, highlighting the rarity and lack of standard treatment for EMH in the spine associated with PCV.
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Objective: The neurosurgical match is a challenging process for applicants and programs alike. Programs must narrow a wide field of applicants to interview and then determine how to rank them after limited interaction. To streamline this, programs commonly screen applicants using United States Medical Licensing Examination (USMLE) Step scores.

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Background: Myxomas, rare benign mesenchymal lesions, are the most common cardiac tumors. Patients may rarely develop hematogenous metastasis to the brain, which can present as new-onset neurological deficits that correlate with multifocal hemorrhagic lesions on imaging. Limited guidelines presently exist for the treatment of such lesions.

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Background: Paragangliomas (PGLs) are rare neoplasms that may be associated with hereditary PGL syndromes and variable risk of metastasis. Middle ear adenomas are extremely rare tumors with no known hereditary predisposition and extremely low risk of metastasis. Although often easily differentiated, they may share clinical and pathological features that misdirect and confuse the diagnosis.

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Objective: Spinal anesthesia (SA) is an alternative to general anesthesia (GA) for lumbar spine surgery, including complex instrumented fusion, although there are relatively few outcome data available. The authors discuss their experience using SA in a modern complex lumbar spine surgery practice to describe its utility and implementation.

Methods: Data from patients receiving SA for lumbar spine surgery by one surgeon from March 2017 to December 2020 were collected via a retrospective chart review.

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Objective: Vessel tapering results in blood flow acceleration at downstream bifurcations (firehose nozzle effect), induces hemodynamics predisposing to aneurysm initiation, and has been associated with middle cerebral artery (MCA) aneurysm presence and rupture status. The authors sought to determine if vessel caliber tapering is a generalizable predisposing factor by evaluating upstream A1 segment profiles in association with aneurysm presence in the anterior communicating artery (ACoA) complex, the most prevalent cerebral aneurysm location associated with a high rupture risk.

Methods: Three-dimensional rotational angiographic studies were analyzed for 68 patients with ACoA aneurysms, 37 nonaneurysmal contralaterals, and 53 healthy bilateral controls (211 samples total).

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Background: Wild-type transthyretin (ATTRwt) amyloid deposition has been found in the ligamentum flavum (LF) of patients undergoing spinal stenosis surgery. Our group previously reported that ATTRwt amyloid is associated with an increased lumbar ligamentum flavum thickness at symptomatic levels that required surgery. A comprehensive evaluation of LF thickness at asymptomatic levels in addition to symptomatic, treated levels has never been performed in ATTRwt patients.

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A 42-year-old woman from a medically underserved community in rural New England was referred by her primary care provider (PCP) for televisit during the coronavirus disease 2019 (COVID-19) pandemic following 2 years of chronic neck pain and numbness in her left hand that was initially concerning for demyelinating disease. Upon further evaluation, it was revealed that she had experienced a traumatic fall with a concussion and symptoms consistent with central cord syndrome but had refused magnetic resonance imaging (MRI) at her initial medical evaluation. On MRI conducted 1 month prior to neurosurgical evaluation she was found to have a disc bulge and 4-mm T2-hyperintense lesion at the C4-C5 level that was consistent with a chronic spinal cord injury secondary to spinal trauma with associated vertebrogenic injury.

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Article Synopsis
  • Researchers found that transthyretin amyloid deposits (ATTRwt) are present in the ligamentum flavum of patients with spinal stenosis, but the effects on ligament thickness were unclear.
  • In a study of 178 patients, those with ATTRwt had a significant increase in ligamentum flavum thickness (4.92 mm) compared to those without (4.00 mm), particularly at the L4-L5 level.
  • The study concluded that ATTRwt is associated with a thicker ligamentum flavum, prompting further investigation into the underlying mechanisms of this relationship.
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Background: Aneurysms at the posterior communicating artery (PCOM) origin represent the most common location on the internal carotid artery (ICA), and are associated with greater recurrence following endovascular treatment. We evaluate the association between ICA angulation in three-dimensional (3D) space and PCOM aneurysmal development, using high-resolution 3D rotational angiography (3DRA) studies.

Methods: 3DRA datasets were evaluated in 70 patients with PCOM aneurysms, 31 non-aneurysmal contralateral, and 86 healthy controls (187 total).

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A 79-year-old woman presented with acute-onset right leg pain in the setting of 3 months of progressive gait deterioration and bilateral leg weakness. On exam she had right lower extremity hyperreflexia and weakness. Lumbar spine magnetic resonance imaging demonstrated L3-L5 central canal stenosis with L4-L5 spondylolisthesis and a previously undiagnosed tethered cord.

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