Publications by authors named "Jeffrey Antwi"
Background: Progressive Supranuclear Palsy (PSP) is a sporadic neurodegenerative disease without a clear geographic prevalence. Cohorts studied in the UK and India showed no higher prevalence of atypical parkinsonism in South Asian patients. We describe the ethnic and racial background of PSP patients in the Greater Toronto Area (GTA), Canada.
View Article and Find Full Text PDFBackground: The impact of age of onset on the presentation of progressive supranuclear palsy phenotypes is not well studied. We hypothesized that there is difference in presentation and phenotype between young- and late-onset PSP.
Objectives: Our aim was to compare phenotypes and rate of change in disability between young-onset PSP (YOPSP) and late-onset PSP (LOPSP).
Background: Global pandemics may limit access to specialized care, delaying diagnosis and treatment of common acute surgical diseases. We analyzed the impact of the novel coronavirus disease 2019 (COVID-19) pandemic on acute appendicitis at an urban tertiary care center. We hypothesize that pandemics are associated with delayed presentation and worsened clinical sequelae, specifically, higher incidences of perforation in children.
View Article and Find Full Text PDFArticle Synopsis
- - The Rossy PSP Centre in Canada is aimed at advancing research in progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS) by collecting extensive clinical data and biological samples from patients every six months.
- - Initial findings from the program, which involved screening 132 patients, showed that the majority had PSP (91) with common symptoms like postural instability, cognitive changes, and Parkinsonism.
- - Future goals include enrolling patients in earlier disease stages, developing new biomarkers, and fast-tracking well-characterized patients into clinical trials to improve diagnosis and treatment strategies for PSP.