Urosdeoxycholic acid in primary sclerosing cholangitis: a meta-analysis and systematic review.

Background And Study Aims: Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with no proven effective medical therapy. Ursodeoxycholic acid (UDCA) was proposed as a potential treatment for this disorder. However, several randomised controlled trials reported conflicting results regarding the usefulness of UDCA.