Publications by authors named "Jefferson H Z Poli"
Article Synopsis
- The study investigates the role of the proliferation marker Ki67 in predicting postoperative outcomes for pituitary adenoma patients, focusing on tumor recurrence and regrowth.
- A cohort of 52 patients who underwent surgery was analyzed, with 23 showing high Ki67 expression (≥3%) and the rest showing low (0-2.9%).
- The findings suggest that while recurrence rates were similar for both groups, the regrowth of tumors was significantly higher in patients with Ki67 ≥3%, indicating the need for closer monitoring in these cases after surgery.
Rationale: Alcohol addiction causes severe problems, and its deprivation may potentiate symptoms such as anxiety. Furthermore, ethanol is a neurotoxic agent that induces degeneration and the consequences underlying alcohol-mediated brain damage remain unclear.
Objectives: This study assessed the behavioral changes during acute ethanol withdrawal periods and determined the levels of DNA damage and reactive oxygen species (ROS) in multiple brain areas.