Publications by authors named "Jeff Bond"
Article Synopsis
- Medulloblastoma is the most common brain tumor in children, and researchers are exploring new treatment options using nifurtimox and tetrathiomolybdate (TM) which both increase reactive oxygen species (ROS) levels in cells.
- The combination of nifurtimox and TM was found to synergistically reduce cell viability and induce apoptosis in medulloblastoma cell lines, confirmed through various analyses including Western blotting and transcriptional profiling.
- The study suggests that this drug combination enhances oxidative stress and activates apoptosis-related pathways, indicating potential for further investigation as a treatment for medulloblastoma.
