Publications by authors named "Jeff Arle"
Objective: To conduct a systematic literature review of spinal cord stimulation (SCS) for pain.
Design: Grade the evidence for SCS.
Methods: An international, interdisciplinary work group conducted literature searches, reviewed abstracts, and selected studies for grading.
Objective: To conduct a systematic literature review of brain neurostimulation for pain.
Design: Grade the evidence for deep brain neurostimulation (DBS).
Methods: An international, interdisciplinary work group conducted a literature search for brain stimulation.
Computational neuroscience is a field that traces its origins to the efforts of Hodgkin and Huxley, who pioneered quantitative analysis of electrical activity in the nervous system. While also continuing as an independent field, computational neuroscience has combined with computational systems biology, and neural multiscale modeling arose as one offshoot. This consolidation has added electrical, graphical, dynamical system, learning theory, artificial intelligence and neural network viewpoints with the microscale of cellular biology (neuronal and glial), mesoscales of vascular, immunological and neuronal networks, on up to macroscales of cognition and behavior.
View Article and Find Full Text PDFBackground: The effects of constant-current deep brain stimulation (DBS) have not been studied in controlled trials in patients with Parkinson's disease. We aimed to assess the safety and efficacy of bilateral constant-current DBS of the subthalamic nucleus.
Methods: This prospective, randomised, multicentre controlled trial was done between Sept 26, 2005, and Aug 13, 2010, at 15 clinical sites specialising in movement disorders in the USA.