Publications by authors named "Jeferson Santiago"

Article Synopsis
  • Clock genes are important for the function of the suprachiasmatic nucleus (SCN) and also play roles in other brain areas; their expression has been studied in various species to understand their functions better.
  • This study focused on the presence of clock genes Per1, Per2, and Cry1 in neurons of the substantia nigra (SN) and subthalamic nucleus (STN) in a diurnal primate, expanding beyond research mainly done on nocturnal rodents.
  • Immunohistochemistry revealed significant presence of Per1 and Per2 in the SN and both these genes in the STN, while Cry1 was not detected in the STN, highlighting the role of these genes in areas linked to motor
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Article Synopsis
  • The study investigates the use of natural products as disinfectants for PMMA dentures, focusing on their potential to prevent denture stomatitis in wearers.
  • After reviewing literature, 46 studies were selected that assessed 39 different natural products for their effectiveness against Candida albicans, with 43 showing positive results.
  • The findings indicate that while natural products, especially those from plants, are promising in lab settings, more clinical research is needed to confirm their effectiveness in real-world scenarios involving denture users.
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Purpose: To evaluate whether complete dentures (CDs) relined with long-term resilient liners (LTRLs) favor better masticatory function, satisfaction, and quality of life among completely edentulous patients compared to conventional CDs.

Materials And Methods: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist and was registered in PROSPERO (the International Prospective Register of Systematic Reviews; CRD42021258700). The population, intervention, comparison, and outcome (PICO) purpose was to determine whether CDs relined with LTRLs favor better masticatory function, satisfaction, and quality of life among completely edentulous patients when compared to CDs.

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Melatonin is a transducer of photic environmental information and participates in the synchronization of various physiological and behavioral phenomena. Melatonin can act directly in several areas of the central nervous system through its membrane receptors coupled to G protein, called MT1 and MT2 receptors. In some structures, such as the retina, hypothalamus and pars tuberalis, the expression of both melatonin receptors shows circadian variations.

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