Publications by authors named "Jeewon Lee"

Due to the extremely high energy density of Li metal, Li metal batteries are regarded as one of the most promising candidates for next-generation energy storage systems. However, interfacial issues, particularly the unstable solid electrolyte interphase (SEI) and lithium dendritic growth, hinder practical application. Herein, we induce an anion-rich interface near the Li metal by introducing positively charged self-assembled monolayers (SAMs) on ceramic-coated separators to simultaneously stabilize the SEI and homogenize the Li deposition.

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A common challenge in nanotechnology is synthesizing nanomaterials with well-defined structures. In particular, it remains a major unresolved challenge to precisely regulate the structure and function of protein nanomaterials, which are structurally diverse, highly ordered, and complex and offer an innovative means that enables a high performance in various nanodevices, which is rarely achievable with other nanomaterials. Here an innovative approach is proposed to fabricating multi-dimensional (0- to 3D) protein nanostructures with functional and structural specialties via molecular-level regulation.

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Article Synopsis
  • Developmental gene regulation relies on long-range communication between enhancers and promoters, which is not fully understood without considering the surrounding chromatin.
  • Researchers studied the Sonic hedgehog (Shh) regulatory region in mouse brains to understand its structural configurations, discovering that it often maintains a compact form that can adopt various layouts regardless of Shh expression.
  • They found that long-range enhancer-promoter interactions occur through both dependent and independent mechanisms of Shh expression, involving specific binding sites and active enhancers, leading to a proposed model that coordinates gene expression patterns.
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Although we have multiple senses, multimedia mainly targets vision and olfaction. To expand the senses impacted by multimedia, olfactory stimulation has been used to enhance the sense of reality. Odors are primarily matched with objects in scenes.

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  • - The study investigated the clinical features and outcomes of younger patients with idiopathic pulmonary fibrosis (IPF), focusing on those under 50 years old compared to older age groups.
  • - Data was analyzed from the National Korean Health Insurance database, revealing that younger IPF patients had fewer comorbidities and were more likely to receive systemic steroids instead of antifibrotic treatments like pirfenidone.
  • - Despite younger patients having a lower mortality risk and no significant increase in acute exacerbation risk, there's a need for better-targeted treatments, including more frequent use of antifibrotics, to improve their health outcomes.
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There is no validated screening measure for children with high-functioning autism spectrum disorder (ASD) in Korea. The purpose of the present study was (1) to examine the reliability and validity of the Korean version of the Autism Spectrum-Child (K-AQ-Child); (2) to find the optimal cut-off value of the K- AQ-Child in the Korean population. A total of 144 children aged 4-11 years (male 80.

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The purpose of the current study was to examine the risk factors of young children's smartphone addiction in a longitudinal study design. Data collected from 313 participants (mean age, 4.5 ± 0.

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Objective: This study aims to investigate the thoughts of the general population regarding life-sustaining treatment for both oneself and family members and to assess the factors associated with those thoughts.

Methods: A total of 1,500 individuals participated in this study by completing a questionnaire consisting of self-reporting items with some instructions, basic demographic information, thoughts on life-sustaining treatment, and psychosocial scales. The disease status was calculated using the Charlson Comorbidity Index.

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Soluble methane monooxygenase (sMMO) oxidizes a wide range of carbon feedstocks (C1 to C8) directly using intracellular NADH and is a useful means in developing green routes for industrial manufacturing of chemicals. However, the high-throughput biosynthesis of active recombinant sMMO and the ensuing catalytic oxidation have so far been unsuccessful due to the structural and functional complexity of sMMO, comprised of three functionally complementary components, which remains a major challenge for its industrial applications. Here we develop a catalytically active miniature of sMMO (mini-sMMO), with a turnover frequency of 0.

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Aim: Short tandem repeats (STRs) are repetitive DNA sequences and highly mutable in various human disorders. While the involvement of STRs in various genetic disorders has been extensively studied, their role in autism spectrum disorder (ASD) remains largely unexplored. In this study, we aimed to investigate genetic association of STR expansions with ASD using whole genome sequencing (WGS) and identify risk loci associated with ASD phenotypes.

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The formation of a stable solid electrolyte interphase (SEI) layer is crucial for enhancing the safety and lifespan of Li metal batteries. Fundamentally, a homogeneous Li behavior by controlling the chemical reaction at the anode/electrolyte interface is the key to establishing a stable SEI layer. However, due to the highly reactive nature of Li metal anodes (LMAs), controlling the movement of Li at the anode/electrolyte interface remains challenging.

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Background: In the myeloid compartment of the tumor microenvironment, CD244 signaling has been implicated in immunosuppressive phenotype of monocytes. However, the precise molecular mechanism and contribution of CD244 to tumor immunity in monocytes/macrophages remains elusive due to the co-existing lymphoid cells expressing CD244.

Methods: To directly assess the role of CD244 in tumor-associated macrophages, monocyte-lineage-specific CD244-deficient mice were generated using cre-lox recombination and challenged with B16F10 melanoma.

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Everyday speech communication often occurs in environments with background noise, and the impact of noise on speech recognition can vary depending on factors such as noise type, noise intensity, and the listener's hearing ability. However, the extent to which neural mechanisms in speech understanding are influenced by different types and levels of noise remains unknown. This study aims to investigate whether individuals exhibit distinct neural responses and attention strategies depending on noise conditions.

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Objective: Successful transition to school is of great importance to children with autism spectrum disorder (ASD). The purpose of this study was to develop a school readiness inventory for Korean children with ASD, and demonstrate its content validity and reliability.

Methods: The Korean School Readiness Inventory (K-SRI) was developed to assess current levels of some fundamental skills needed for attending school for children with ASD.

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Objective: The purpose of the current study was to examine the prevalence of attention deficit hyperactivity disorder (ADHD) in girls with central precocious puberty.

Method: Girls with central precocious puberty were prospectively recruited from the pediatric clinic. Screening was done with ADHD Rating Scale (ADHD-RS) and Child Behavior Checklist (CBCL).

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The present study examined the prevalence of autism spectrum disorder (ASD) in intellectually capable children with attention deficit hyperactivity disorder (ADHD). Retrospective chart review on 103 children (mean age= 7.83 ± 1.

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Article Synopsis
  • Existing urinary cancer markers face challenges due to the complex urine environment, which affects conventional immunoassays' effectiveness.
  • The researchers developed a new 3D-plus-3D (3p3) immunoassay method for detecting urinary cancer markers using 3D-antibody probes, improving marker capture in a 3D solution.
  • This new method demonstrated perfect sensitivity and specificity for diagnosing prostate cancer by detecting the related protein, suggesting potential for broader clinical application and improved cancer diagnostics.
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Objective: The purpose of the present study was to develop and validate the Korean version of the clinician-administered KSADSCOMP, which is the recently updated, web-based computerized version of the Kiddie Schedule for Affective Disorders and Schizophrenia for school-age children (KSADS).

Methods: A total of 71 participants (mean age=12.04±3.

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Objective: This study examined the factors influencing the mental health and stress of individuals during the coronavirus disease-2019 (COVID-19) pandemic.

Methods: A total of 600 participants were enrolled in this anonymous questionnaire survey that included questions on their demographic profiles and experiences related to the COVID-19 pandemic. The COVID-19 Stress Scale for Korean People (CSSK), Warwick- Edinburgh Mental Wellbeing Scale, Generalized Anxiety Disorder-7, Patient Health Questionnaire-9, Insomnia Severity Index, and Multidimensional Scale of Perceived Social Support were used.

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Composite solid electrolytes (CSEs) are newly emerging components for all-solid-state Li-metal batteries owing to their excellent processability and compatibility with the electrodes. Moreover, the ionic conductivity of the CSEs is one order of magnitude higher than the solid polymer electrolytes (SPEs) by incorporation of inorganic fillers into SPEs. However, their advancement has come to a standstill owing to unclear Li-ion conduction mechanism and pathway.

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  • ADHD in adolescents is linked to depressive disorders, and there's little research on the safety of using methylphenidate (MPH) with SSRIs together, which this study aims to address.
  • A nationwide study in South Korea compared adolescents treated with MPH alone to those receiving both MPH and SSRIs, focusing on various health outcomes while controlling for other factors.
  • Results indicate that using MPH with SSRIs is generally safe, with a notable finding that fluoxetine is associated with a lower risk of tic disorder compared to escitalopram, but most outcomes showed no significant differences.
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The purpose of the present study was to examine the validity of the Korean version of the parent and youth self-administered versions of the KSADS-COMP (The Kiddie Schedule for Affective Disorders and Schizophrenia for school-age children). To assess the criterion validity of the KSADS-COMP, diagnoses made by the selfadministered KSADS-COMP were compared to the gold-standard diagnoses made by the child-adolescent psychiatrists in 41 participants (mean age=14.93 ± 2.

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Background: Methylphenidate (MPH) is the most frequently prescribed medication for the treatment of attention deficit hyperactivity disorder (ADHD). However, the safety of its long-term use remain unclear. In particular, real-world evidence of long-term MPH treatment regarding the risk of depression, conduct disorders, and psychotic disorders in children and adolescents is needed.

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The Audiology Practice Standards Organization (APSO) which was formed in 2017 set out to compile basic services that audiologists within the field should adhere to in their practice. The second standard of the APSO is the Hearing Aid Fitting Standard for Adult and Geriatric Patients. Among the services outlined for an adult hearing aid fitting, orientation is discussed.

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