Nociceptive behavior following hindpaw burn injury in young rats: response to systemic morphine.

Objective: Develop a burn injury model in young age rats.

Background: Management of pain after burn injury in pediatric patients is an unresolved clinical issue.

Methods: A burn injury model in young rats of 3-4 weeks old was developed by briefly immersing the dorsal part of the right hindpaw in a hot water bath (85°C) for 12 seconds under pentobarbital anesthesia.