Publications by authors named "Jeeun Lee"
Background And Purpose: Cognitive and behavioral changes are common in amyotrophic lateral sclerosis (ALS), with about 15% of patients presenting with overt frontotemporal dementia and 30%-50% with varying degrees of impairments. We aimed to develop and validate the Korean version of the Edinburgh Cognitive and Behavioral ALS Screen (ECAS-K), a brief multidomain assessment tool developed for ALS patients with physical disability.
Methods: We developed the ECAS-K according to the translation guidelines, and administered it to 38 patients with ALS and 26 age- and education-level-matched controls.
Background And Purpose: Serum insulin-like growth factor-1 (IGF-1) is known to have a neuroprotective effect. This study aimed to determine the effects of serum IGF-1 on the severity and clinical outcome of acute ischemic stroke (AIS).
Methods: This study included 446 patients with AIS who were admitted to Hallym University Sacred Heart Hospital within 7 days of stroke onset from February 2014 to June 2017.
Article Synopsis
- CSF biomarkers are crucial for diagnosing and predicting Alzheimer's disease, but current cut-off values may be misleading due to including high-risk controls.
- This research aimed to develop more accurate models by analyzing CSF biomarker data from participants in the Alzheimer’s Disease Neuroimaging Initiative.
- Key findings reveal that factors like age, ε4 status, and sex significantly affect CSF biomarker levels, leading to improved prediction models for determining the risk of mild cognitive impairment progressing to Alzheimer's.