Publications by authors named "Jeesun Lee"

This study investigated between-person associations among PTSD symptoms, fear of emotion, and perceived couple communication difficulties in a dyadic context among 64 trauma-exposed, mixed gender community couples (N = 128 individuals) using the Actor-Partner Interdependence Mediation Model. Individuals with higher PTSD symptoms endorsed greater fear of their emotions (β = .72; β = .

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  • Preeclampsia (PE) is a pregnancy-related disorder caused by issues with the placenta, making it challenging for clinicians to accurately diagnose due to a lack of standard diagnostic criteria.
  • This study explored the use of computational pathology to differentiate between PE and normal placentas by analyzing 168 placental images from two hospitals, employing both unsupervised and supervised learning techniques.
  • The resulting prediction model demonstrated good performance, achieving a sensitivity of 77.3% and specificity of 71.1%, indicating its potential effectiveness for identifying PE placentas in clinical settings.
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Spillover from interparental conflict (IPC) to the parent-child relationship is a risk factor for adolescent emotional, social, and behavioral maladjustment. Parental depression increases the risk for more frequent and intense IPC over periods of months to years, but relatively little is known about whether parental depressive symptoms increase the risk for IPC and/or the propensity for spillover on short timescales. Using daily diary methods, we tested two hypotheses to evaluate whether parental depressive symptoms predict increased risk for IPC spillover: (a) a , in which higher levels of parental depressive symptoms are associated with a greater tendency to experience IPC, which elevates risk for spillover, and (b) a , in which parental depressive symptoms strengthen the within-person linkage between daily couple conflict and poorer parent-adolescent relations.

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  • The study investigates the effects of maternal COVID-19 vaccination and infection on the immune responses of both mothers and their newborns, highlighting a lack of data on neonatal outcomes from pre-pregnancy vaccination.
  • Results show that mothers vaccinated before pregnancy pass on stronger antiviral protection to their infants compared to those who were vaccinated or infected during pregnancy.
  • The findings suggest that pre-pregnancy vaccination contributes significantly to neonatal immunity against SARS-CoV-2 by enhancing the transfer of neutralizing antibodies via the placenta.
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  • Ultrasonographic soft markers are normal variations in fetal imaging, and guidelines suggest analyzing fetal anatomy to decide if further genetic testing (like antenatal karyotyping) is needed.
  • This systematic review assessed the significance of chromosomal microarray analysis (CMA) for pregnancies with isolated soft markers and a normal karyotype, analyzing over 3,300 articles.
  • The review found that 2.0% of cases had pathogenic copy number variants, with the highest occurrence in cases with short femur (3.9%), indicating that CMA might help in risk assessment and counseling for these pregnancies.
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Objective: To evaluate the risk of metabolic syndrome (MS) after recurrent pregnancy loss (RPL) using UK Biobank data. A history of pregnancy loss is associated with the development of cardiovascular diseases in the future. However, the association between RPL and subsequent MS is poorly understood.

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Objective: Hypertensive disease during pregnancy increases the risk of maternal morbidity and mortality and leads to the development of multi-organ dysfunction, including kidney dysfunction. Complicated pregnancies require careful postpartum management to prevent sequelae. It is believed that kidney injury can consistently occur even after delivery; therefore, defining the chronicity and endpoint is essential for establishing diagnostic criteria.

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Background And Purpose: A recent international expert consensus opinion suggested that metabolic dysfunction-associated fatty liver disease (MAFLD) replaces nonalcoholic fatty liver disease (NAFLD), since MAFLD is a better predictor of cardiovascular disease. We estimated the prevalence of FLD in fertile females and evaluated the clinical impact of either NAFLD or MAFLD on maternal and fetal outcomes during subsequent pregnancy.

Methods: The study population included fertile females who underwent health examinations and became pregnant within 1 year of health examination.

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Background: Early intervention to reduce the impact of adverse events (AEs) may improve patients' quality of life and enable optimal treatment duration.

Methods: This nationwide, multicenter, prospective, longitudinal, 1-year observational study investigated patients' self-management of AEs associated with targeted therapy for advanced renal cell carcinoma (RCC) and explored corresponding outcomes, including treatment duration and patient-reported outcomes (PROs).

Results: We enrolled 77 advanced RCC patients (mean age 62 years) treated with a first targeted therapy.

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Purpose: Research on the role of insulin resistance (IR) in breast cancer risk in premenopausal women is scarce. We aimed to investigate the relationship between IR and the development of breast cancer in premenopausal women.

Methods: We analyzed the prospective association of IR and incident breast cancer in premenopausal women without breast cancer at baseline using a subsample of the Kangbuk Samsung Health Study.

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Background/aim: To evaluate the clinical desire for pressurized intraperitoneal aerosol chemotherapy (PIPAC) in South Korea.

Patients And Methods: We performed an online survey on surgical oncologists between November and December 2019 using a questionnaire consisting of 20 questions.

Results: A total of 164 respondents answered the questionnaire.

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Background: The build-up of advanced glycation end products (AGEs) is one of important factor of skin aging. Natural compounds with anti-glycation activities might have great anti-aging potential.

Aims: The objective of this study was to evaluate an anti-glycation effects of methyl gallate as a potent ingredient for anti-aging.

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Purpose: In 2015, the South Korean government legislated the Act for the Improvement of Training Conditions and Status of Medical Residents (Medical Resident Act). This study investigated changes in the working and learning environment pre- and post-implementation of the Medical Resident Act in 2017, as well as changes in training conditions by year post-implementation..

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Study Objective: To evaluate suture complication rates and surgical outcomes according to the nonabsorbable suture materials used in vaginal uterosacral ligament suspension (USLS) surgery. Multifilament polyester (polyethylene terephthalate [PET]) and monofilament polypropylene (PP) sutures were compared.

Design: Retrospective cohort study.

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Background: Accurate prediction of fall likelihood is advantageous for instituting fall prevention program in rehabilitation facilities.

Objective: This study was designed to determine the clinical measures, which can predict the risk of fall events in a rehabilitation hospital.

Methods: Medical records of 166 patients (114 males and 52 females) who were hospitalized in an adult inpatient unit of a rehabilitation hospital were retrospectively analyzed for this study.

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Background: Solar ultraviolet radiation (UV) induces DNA damages in skin via direct absorption of UVB or indirectly by photosensitization mediated through UVA. Recent findings have revealed that UVA induces cyclobutane pyrimidine dimer (CPD) generation via chemiexcitation in melanocytes hours after the exposure. This UVA-induced delayed CPD (dark CPD) constitutes the majority of CPD in melanocytes.

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Background: Although Asian people are known to have lower bone mass than that of Caucasians, little is known about coffee-associated bone health in Asian. This study aimed to assess the relationship between coffee consumption and bone mineral density (BMD) in Korean premenopausal women.

Methods: Data were obtained from the Fourth Korea National Health and Nutrition Examination Survey 2008-2009.

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Despite the academic and industrial importance of the chemical reaction between carbon dioxide (CO(2)) and alkanolamine, the delicate and precise monitoring of the reaction dynamics by conventional one-dimensional (1D) spectroscopy is still challenging, due to the overlapped bands and the restricted static information. Herein, we report two-dimensional infrared correlation spectroscopy (2D IR COS) and principal component analysis (PCA) on the reaction dynamics of a sterically hindered amine, 2-[(1,1-dimethylethyl)amino]ethanol (TBAE) and CO(2). The formation of carbonate rather than carbamate species, which contribute to the unusual high working capacity of ∼1 mole CO(2) per mole of TBAE at 40 °C, occurs through deprotonation of the hydroxyl group, protonation on the nitrogen atom of the amino group, and formation of a carbonate species due to the steric hindrance of the tert-butyl group.

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Interesterification of a 60:40 (wt/wt) mixture of olive oil and fully hydrogenated canola oil was carried out in a batch reactor using a commercial immobilized lipase from Thermomyces lanuginose as a biocatalyst. The effects of a stepwise change of temperature on the degree of conversion, the solid fat content (SFC) of the products, and the residual activity of the enzyme were investigated. As a reference condition, an interesterification trial was conducted at a constant temperature of 70 degrees C for 48 h.

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