Publications by authors named "Jeehun Kim"

Background: Dixon-based magnetic resonance imaging (MRI) intramuscular proton density fat fraction (PDFF) is a potentially useful imaging biomarker of muscle quality. However, multi-vendor, multi-site reproducibility of intramuscular PDFF quantification, required for large clinical studies, can be strongly dependent on acquisition and processing. The purpose of this study was (I) to develop a 6-point Dixon MRI-based acquisition and processing technique for reproducible multi-vendor, multi-site quantification of thigh intramuscular PDFF; and (II) to evaluate the ability of the technique to detect differences in thigh muscle status between operated .

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Articular cartilage damage and degeneration are among hallmark manifestations of joint injuries and arthritis, classically osteoarthritis. Cartilage compositional MRI (Cart-C MRI), a quantitative technique, which aims to detect early-stage cartilage matrix changes that precede macroscopic alterations, began development in the 1990s. However, despite the significant advancements over the past three decades, Cart-C MRI remains predominantly a research tool, hindered by various technical and clinical hurdles.

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Bone marrow edema-like lesions (BMEL) in the knee have been linked to the symptoms and progression of osteoarthritis (OA), a highly prevalent disease with profound public health implications. Manual and semi-automatic segmentations of BMELs in magnetic resonance images (MRI) have been used to quantify the significance of BMELs. However, their utilization is hampered by the labor-intensive and time-consuming nature of the process as well as by annotator bias, especially since BMELs exhibit various sizes and irregular shapes with diffuse signal that lead to poor intra- and inter-rater reliability.

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Background: Knee tissues such as tendon, ligament and meniscus have short T* relaxation times and tend to show little to no signal in conventional magnetic resonance acquisitions. An ultrashort echo time (UTE) technique offers a unique tool to probe fast-decaying signals in these tissues. Clinically relevant factors should be evaluated to quantify the sensitivity needed to distinguish diseased from control tissues.

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Article Synopsis
  • Magnetization-prepared gradient-echo sequences can pick up unwanted signal interference from T recovery during imaging, which traditional paired RF phase cycling can remove but at the cost of longer scan times.
  • This study introduces a new unpaired phase cycling method that maintains accuracy without doubling the scan time, tested through phantom and human knee imaging at 3T.
  • Results show that the unpaired approach achieves similar or better quantitative accuracy and reproducibility compared to paired methods, making it a promising option for faster and more efficient imaging.
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Purpose: To analyze the visual acuity, contrast sensitivity, and target deviations in patients who had laser in situ keratomileusis (LASIK) for primary hyperopia with the ablation centered on the coaxially sighted corneal light reflex.

Setting: University-based refractive surgery practice.

Methods: Retrospective review comprised 37 consecutive patients (61 eyes) who had LASIK for hyperopia with the LADARVision 4000 excimer laser (Alcon Laboratories).

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