Risk Factors and Outcomes of Bloodstream Infections Among People With Human Immunodeficiency Virus: A Longitudinal Cohort Study From 2000 to 2017.

Background: Bloodstream infections (BSIs) among people with human immunodeficiency virus (PWH) remain a poorly studied source of morbidity and mortality. We characterize the epidemiology, microbiology, and clinical outcomes including reinfection, hospitalization, and mortality rates of both community-acquired and hospital-acquired BSI in PWH.

Methods: We identified all BSI, between January 1, 2000 and December 31, 2017 in PWH in care at Southern Alberta Clinic, by linking data from laboratory and clinical databases.

A longitudinal population-based study of predictors of mortality from bloodstream infections in Calgary, Alberta, Canada.

To study the predictors of mortality from nine major pathogens causing approximately 70% of cases over a 7-year period. A population-based surveillance cohort of all adult and pediatric patients in the Calgary Zone with an initial episode of bloodstream infections (BSI). The 1-year mortality was 29.

Age and sex-specific incidence rates of group A streptococcal pharyngitis between 2010 and 2018: a population-based study.

Group A streptococcus (GAS) pharyngitis is a common clinical infection with significant morbidity but remains understudied. We sought to assess the rates of testing and incidence of GAS pharyngitis in Calgary, Alberta based on age and sex. A total of 1,074,154 tests were analyzed (58.

Longitudinal evaluation of risk factors and outcomes of blood stream infections due to s species in persons with HIV: An observational cohort study.

Background: Staphylococcal blood stream infections (SBSI) are a significant cause of morbidity and mortality, however there is little data on such infections in persons with HIV (PWH) in the combination antiretroviral therapy era, particularly when divided by species; methicillin-sensitive (MSSA) and methicillin-resistant (MRSA) and coagulase-negative (CoNS).

Methods: Using linked longitudinal clinical and microbiologic databases, all cases of SBSI in PWH accessing care at Southern Alberta Clinic were identified and demographic features and outcomes characterized. We compared participants with SBSI to those with no SBSI and determined the 1-year all-cause mortality following SBSI and longitudinally over the study period.

Community data of adults fasting for lipid and diabetes tests in Calgary, Alberta from 2010 to 2016.

Data presented in this data article include the proportion and counts of community-based adult men and women who fasted for various lipid and diabetes screening-related tests from January 2010 to June 2016 in Calgary, Alberta, Canada. This data set was collected from Calgary Laboratory Service׳s Laboratory Information System, and included 3,003,667 testing encounters (1,447,720 testing encounters for men and 1,555,947 testing encounters for women) over the age of 18 years, who fasted for a lipid profile, lipid+random blood glucose (RBG), lipid+hemoglobin A (HbA), lipid+RBG+HbA, lipid+fasting blood glucose (FBG), lipid+FBG+RBG, lipid+FBG+HbA, or lipid+FBG+RBG+HbA. Data are related to "Proportion of adults fasting for lipid testing relative to guideline changes in Alberta" (Ma et al.

Evaluation of a provincial intervention to reduce redundant hemoglobin A1c testing.

Background: The Canadian Diabetes Association recommends testing most individuals with diabetes mellitus using HbA1c once every 3months. In Alberta, Canada, a provincial intervention to reduce inappropriate HbA1c test orders was implemented to align with this guideline, where only one HbA1c test request every 90days for most individuals can be processed. Here, we evaluated the provincial intervention to reduce redundant HbA1c testing in Alberta.

Proportion of adults fasting for lipid testing relative to guideline changes in Alberta.

Background: Guidelines have historically recommended measuring lipid profile tests in a fasting state. However, in April 2011 and 2014, the Canadian city of Calgary and its province of Alberta, respectively, have changed their lipid guidelines to allow testing for individuals in any fasting state; several years prior to the release of the 2016 Canadian Cardiovascular Society and Hypertension Canada guidelines. The purpose of this study was to document the proportion of individuals in Calgary who fasted for a lipid encounter in relation to the change in various guidelines and policies.

Canadian family physician knowledge and attitudes toward laboratory utilization management.

Objectives: Mitigation of unnecessary and redundant laboratory testing is an important quality assurance priority for laboratories and represents an opportunity for cost savings in the health care system. Family physicians represent the largest utilizers of laboratory testing by a large margin. Engagement of family physicians is therefore key to any laboratory utilization management initiatives.

A population study of fasting time and serum prostate-specific antigen (PSA) level.

Prostate cancer is one of the most common cancers in men. Traditional screening and diagnostic methods include digital rectal examinations (DREs), biopsies and serum prostate-specific antigen (PSA) tests, with the latter being the more popular. PSA is a biomarker for prostate cancer; however, it is highly sensitive to external factors as well as other prostate diseases.