Brief Cognitive Tests for Distinguishing Clinical Alzheimer-Type Dementia From Mild Cognitive Impairment or Normal Cognition in Older Adults With Suspected Cognitive Impairment.

Background: The accuracy and harms of brief cognitive tests for identifying clinical Alzheimer-type dementia (CATD) are uncertain.

Purpose: To summarize evidence on accuracy and harms of brief cognitive tests for CATD in older adults with suspected cognitive impairment.

Data Sources: Electronic bibliographic databases (from inception to November 2019) and systematic review bibliographies.

Accuracy of Biomarker Testing for Neuropathologically Defined Alzheimer Disease in Older Adults With Dementia.

Background: Biomarker accuracy for Alzheimer disease (AD) is uncertain.

Purpose: To summarize evidence on biomarker accuracy for classifying AD in older adults with dementia.

Data Sources: Electronic bibliographic databases (searched from January 2012 to November 2019 for brain imaging and cerebrospinal fluid [CSF] tests and from inception to November 2019 for blood tests), ClinicalTrials.

Benefits and Harms of Prescription Drugs and Supplements for Treatment of Clinical Alzheimer-Type Dementia.

Background: Effects of drug treatment of clinical Alzheimer-type dementia (CATD) are uncertain.

Purpose: To summarize evidence on the effects of prescription drugs and supplements for CATD treatment.

Data Sources: Electronic bibliographic databases (inception to November 2019), ClinicalTrials.

Psychological and Behavioral Interventions for Managing Insomnia Disorder: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians.

Background: Psychological and behavioral interventions are frequently used for insomnia disorder.

Purpose: To assess benefits and harms of psychological and behavioral interventions for insomnia disorder in adults.

Data Sources: Ovid MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and PsycINFO through September 2015, supplemented with hand-searching.

Pharmacologic Treatment of Insomnia Disorder: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians.

Background: Pharmacologic interventions are often prescribed for insomnia disorder.

Purpose: To assess the benefits, harms, and comparative effectiveness of pharmacologic treatments for adults with insomnia disorder.

Data Sources: Several electronic databases (2004-September 2015), reference lists, and U.

Intermediate- and Long-Term Cognitive Outcomes After Cardiovascular Procedures in Older Adults: A Systematic Review.

Background: Risks for intermediate- and long-term cognitive impairment after cardiovascular procedures in older adults are poorly understood.

Purpose: To summarize evidence about cognitive outcomes in adults aged 65 years or older at least 3 months after coronary or carotid revascularization, cardiac valve procedures, or ablation for atrial fibrillation.

Data Sources: MEDLINE, Cochrane, and Scopus databases from 1990 to January 2015; ClinicalTrials.

Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an American College of Physicians Clinical Guideline.

Background: Optimum management to prevent recurrent kidney stones is uncertain.

Purpose: To evaluate the benefits and harms of interventions to prevent recurrent kidney stones.

Data Sources: MEDLINE, Cochrane, and other databases through September 2012 and reference lists of systematic reviews and randomized, controlled trials (RCTs).

Pharmacologic therapy for primary restless legs syndrome: a systematic review and meta-analysis.

Importance: Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and a distressing, irresistible urge to move them. We conducted a systematic review to evaluate efficacy, safety, and comparative effectiveness of pharmacologic treatments for primary RLS.

Evidence Acquisition: We included randomized controlled trials (RCTs), published in English, reporting efficacy outcomes and harms of pharmacologic treatments for primary RLS of at least 4 weeks' duration.

Participation after multidisciplinary rehabilitation for moderate to severe traumatic brain injury in adults: a systematic review.

Objective: To determine the effectiveness and comparative effectiveness of multidisciplinary rehabilitation programs for moderate to severe traumatic brain injury (TBI) in improving participation-related outcomes in adults. This article presents results of select key questions from a recent Agency for Healthcare Quality and Research comparative effectiveness review.

Data Sources: MEDLINE, Cochrane Central Register of Controlled Trials, and PsycINFO; hand searches of previous relevant reviews.