Contemporary practice patterns in the surgical management of Hirschsprung's disease.

Background: Many options exist in the surgical management of Hirschsprung's disease (HD). To gain insight into contemporary management, we queried pediatric surgeons listed in the American Pediatric Surgical Association Directory on their management for the typical baby with HD.

Methods: Surveys were sent electronically to the surgeons concerning a typical newborn diagnosed with HD.

Natural history of nonoperative management for grade 4 and 5 liver and spleen injuries in children.

Purpose: Nonoperative management is standard treatment of blunt liver or spleen injuries. However, there are few reports outlining the natural history and outcomes of severe blunt hepatic and splenic trauma. Therefore, we reviewed our experience with nonoperative management of grade 4 or 5 liver and spleen injuries.

Successful percutaneous drainage of duodenal hematoma after blunt trauma.

Duodenal hematoma after blunt trauma is usually treated nonoperatively with bowel rest, nasogastric tube suction, and intravenous hydration. We report a case in which obstructive symptoms persisted despite more than 2 weeks of conservative management. An ultrasound-guided percutaneous drain was placed, with successful resolution of symptoms.

Presumed appendiceal abscess discovered to be ruptured Meckel diverticulum following percutaneous drainage.

A Meckel diverticulum is an embryonic remnant of the omphalomesenteric duct that occurs in approximately 2% of the population. Most are asymptomatic; however, they are vulnerable to inflammation with subsequent consequences including diverticulitis and perforation. We report an 11-year-old boy who underwent laparoscopic appendectomy for perforated appendicitis at an outside institution.

Enhanced activity of hu14.18-IL2 immunocytokine against murine NXS2 neuroblastoma when combined with interleukin 2 therapy.

Established s.c. NXS2 murine neuroblastoma tumors exhibited transient resolution after suboptimal therapy using the hu14.