Expression of Generalized Anxiety Disorder Across the Lifespan.

In generalized anxiety disorder (GAD), both the associated symptoms and worry content have been shown to vary as a function of age (Jeste et al., 2005; Portman et al., 2011).

Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis.

Objectives: We developed a patient-reported outcome (PRO) instrument to assess the skin-related quality of life in patients with systemic sclerosis (SSc).

Methods: Participants with SSc provided input on skin-related health effects through focus groups. We developed items for scleroderma skin PRO (SSPRO) to encompass these effects.