Baseline insulin/glucose ratio as a marker for the clinical course of hyperglycemic critically ill children treated with insulin.

Objective: The objective of this study was to investigate the relations of baseline insulin/glucose ratio to the clinical course of critically ill children. Such information will provide insight into the pathophysiologic mechanisms leading to hyperglycemia and will optimize preventive and therapeutic measures for hyperglycemia in critically ill children.

Methods: Sixty-four consecutively admitted critically ill children with hyperglycemia, defined as a blood glucose level higher than 8 mmol/L (>145 mg/dL) and treated with insulin according to a glucose-control protocol, were included.

Management of hyperglycemia in the pediatric intensive care unit; implementation of a glucose control protocol.

Objective: To evaluate a stepwise nurse-driven glucose control protocol for the treatment of hyperglycemia in critically ill pediatric patients.

Setting: Academic pediatric intensive care unit.

Design: Prospective observational study.