Background: Estimates of influenza-associated hospitalization are severely limited in low- and middle-income countries, especially in Africa.
Objectives: To estimate the national number of influenza-associated severe acute respiratory illness (SARI) hospitalization in Rwanda.
Methods: We multiplied the influenza virus detection rate from influenza surveillance conducted at 6 sentinel hospitals by the national number of respiratory hospitalization obtained from passive surveillance after adjusting for underreporting and reclassification of any respiratory hospitalizations as SARI during 2012-2014.