Publications by authors named "Jeanne M Gunzinger"

Article Synopsis
  • Paediatric uveitis, while rare, can have diverse causes and impact different eye segments; this study aims to analyze demographic data from a Swiss cohort to improve diagnosis and treatment.
  • A retrospective study spanning from January 2012 to June 2022 was conducted on patients under 18, revealing that more than half of the 93 analyzed patients were female, with a mean age of 12 years and a majority diagnosed with non-infectious uveitis.
  • The findings highlighted a strong association between bilateral uveitis and non-infectious causes, with significant differences in visual acuity based on the type of uveitis, indicating the importance of understanding local demographics for effective management.
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Purpose: To evaluate the efficacy of a subthreshold micropulse laser (SML) in patients with central serous chorioretinopathy (CSCR).

Methods: Retrospective clinical study conducted at the Departments of Ophthalmology at a university and a municipal hospital in Zurich, Switzerland. We enrolled acute and chronic CSCR patients with persistent subretinal fluid (SRF) treated with SML.

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Aims Of The Study: Vitamin A deficiency retinopathy is a potentially blinding disease. In developed countries, vitamin A deficiency due to malnutrition is rare. However, vitamin A deficiency can be caused by malabsorption resulting from bowel resection or medication.

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Background: Solar and laser-associated retinopathies are rare occurrences. The two retinopathies are both photo-induced but differ in the involved intensity and duration of exposure. The purpose of this study was to evaluate the clinical features and natural course of these two entities, with a focus on the changes in the outer retina over time.

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To investigate associations and predictive factors between macular neovascularization (MNV) lesion variants and drusen types in patients with treatment-naïve neovascular age-related macular degeneration (AMD). Methods: Multimodal imaging was retrospectively reviewed for druse type (soft drusen, subretinal drusenoid deposits (SDDs) or mixed) and MNV type (MNV 1, MNV 2, MNV 1/2 or MNV 3). The Consensus on Neovascular AMD Nomenclature (CONAN) classification was used for characterizing MNV at baseline.

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Article Synopsis
  • TAVI is a less invasive option for elderly patients with aortic valve stenosis, but it can potentially lead to retinal emboli.
  • A study followed 28 patients for two years to assess changes in retinal health using OCTA scans before and after the procedure.
  • Although new capillary lesions were found in some patients post-TAVI, overall vision remained stable, indicating that ocular blood flow regulation might be effective in these individuals.
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Background: To describe cases of retinal vascular events shortly after administration of mRNA or adenoviral-vectored COVID-19 vaccines.

Design: Retrospective, multicenter case series.

Methods: Six cases of retinal vascular events shortly after receiving COVID-19 vaccines.

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To evaluate efficacy of eplerenone therapy vs. observation on resolution of subretinal fluid (SRF) in patients with acute and chronic central serous chorioretinopathy (CSCR) in routine clinical practice. Retrospective comparative case series of eyes diagnosed with CSCR treated with eplerenone or observation.

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The purpose of the study was to analyze imaging findings in spectral domain en face optical coherence tomography (SD OCT) in patients with laser-induced and solar maculopathies focusing on the possible regeneration of the ellipsoid zone. In a retrospective case series of 3 patients (4 eyes) with solar maculopathy and 2 patients (3 eyes) with laser-induced maculopathy who underwent a comprehensive ocular examination, ellipsoid zone (EZ) was segmented from SD OCT data. Evaluation of EZ in en face OCT revealed a hyporeflective lesion surrounded by a hyperreflective border.

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Purpose: To report the findings of anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM) in two patients with peripheral hypertrophic subepithelial corneal degeneration (PHSD).

Methods: Case series by restrospective chart review and imaging analysis of AS-OCT and IVCM.

Results: Slit lamp examination of the two patients revealed a bilateral subepithelial-elevated fibrous tissue of the superior-nasal quadrant, as well as inferior-nasal in one of the patients.

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Background: Hybrid positron emission tomography/magnetic resonance imaging (PET/MRI) shows high potential for patients with oropharyngeal cancer. Dental implants can cause substantial artifacts in the oral cavity impairing diagnostic accuracy. Therefore, we evaluated new MRI sequences with multi-acquisition variable-resonance image combination (MAVRIC SL) in comparison to conventional high-bandwidth techniques and in a second step showed the effect of artifact size on MRI-based attenuation correction (AC) with a simulation study.

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