Synopsis of recent research by authors named "Jeanne Lanoir"
- Jeanne Lanoir's research primarily investigates the distribution and density of serotonin (5-HT) receptors, particularly the 5-HT1A subtype, in various regions of the brain, focusing on developmental changes in knockout mouse models.
- Her 2006 study revealed a reduced density of functional 5-HT1A receptors in the brain, medulla, and spinal cord of monoamine oxidase-A knockout (MAO-A KO) mouse neonates, highlighting potential alterations related to elevated serotonin levels.
- The findings suggest that both autoreceptors in the dorsal raphe and postsynaptic 5-HT1A receptors in target structures may be affected differently during early postnatal development, emphasizing the complexity of serotonin signaling in the context of genetic alterations.
