Publications by authors named "Jeanmarie Schied"
Background: Influenza acts synergistically with bacterial co-pathogens. Few studies have described co-infection in a large cohort with severe influenza infection.
Objectives: To describe the spectrum and clinical impact of co-infections.
Severe Influenza in 33 US Hospitals, 2013-2014: Complications and Risk Factors for Death in 507 Patients.
Infect Control Hosp Epidemiol
November 2015
Article Synopsis
- Influenza A (H1N1) pdm09 was the main strain in the US during the 2013-2014 season, but little was known about severe cases
- A study analyzed data from 33 hospitals, tracking 507 severely ill patients to identify mortality risk factors and patient characteristics
- Key findings revealed that older age, male sex, recent chemotherapy for malignant tumors, and higher organ failure scores were linked to higher mortality among adult patients with severe influenza.
Article Synopsis
- The report details the creation and testing of a new RNA sample prep system, TruTip, for nasopharyngeal samples using a unique pipette tip design with a nucleic acid binding matrix.
- TruTip demonstrated extraction efficiencies comparable to the automated QIAcube method, successfully detecting influenza A and B at specific gene copy levels.
- Preclinical tests showed a 98% detection accuracy for TruTip compared to the established easyMAG extraction method, highlighting its potential for automation and adaptability.