Early electrophysiological abnormalities and clinical neuropathy: a prospective study in patients with type 1 diabetes.

Objective: The aim of this study was to elucidate whether subclinical nerve dysfunction as reflected by neurophysiological testing predicts the development of clinical neuropathy in patients with type 1 diabetes.

Research Design And Methods: Fifty-nine patients were studied twice with neurophysiological measurements at baseline and at follow-up. At baseline, patients were 15.