Preliminary studies of the effects of vascular adhesion protein-1 inhibitors on experimental corneal neovascularization.

Vascular adhesion protein-1 (VAP-1) controls the adhesion of lymphocytes to endothelial cells and is upregulated at sites of inflammation. Moreover, it expresses amine oxidase activity, due to the sequence identity with semicarbazide-sensitive amine oxidase. Recent studies indicate a significant role for VAP-1 in neovascularization, besides its contribution to inflammation.

Recently recognized cases of ophthalmofilariasis in Hungary.

Purpose: To report four cases of zoonotic ophthalmodirofilariasis infection caused by Dirofilaria repens in Hungary.

Methods: Four cases of ophthalmofilariasis have been treated at our department during the last 14 months. A subconjunctival moving worm was observed by slit lamp biomicroscopy in two cases.

[Tumoral sinuses or vascular channels in tumors. Legacy of B. Kellner].

The re-discovery of the tumor cell-lined vascular channels and the possible pathomechanism (vasculogenic mimicry) earned major attention in the literature. This phenomenon is known for 60 years following B.Kellner, later supported by several groups, however its significance is still not known.